Studies on mechanism of lipid uptake into teleost oocytes

在硬骨鱼中，在其生长阶段，卵母细胞中积累了大量的脂肪和蛋白质；它们后来被发育中的胚胎和幼体用作能量和营养资源。然而，关于这类脂类的来源以及它们积聚到卵母细胞中的机制还知之甚少。在本研究中，我们旨在从分子水平上阐明其作用机制。因此，我们找出了影响鱼类卵母细胞摄取脂肪的各种因素，并提出了一个新的卵母细胞脂肪转化模型。

In teleost fishes, high amounts of lipids and proteins are accumulated in oocytes during their growth phase ; they are later utilized as energy and nutrient resources by developing embryos and larvae. However, little is known about the origin of such lipids and the mechanisms underlying their accumulation into oocytes. In the present study, we aimed to clarify the mechanisms at the molecular levels. As the results, we identified various factors involved in the lipid uptake into fish oocytes, and proposed a new model for the oocyte lipidation.