Studies on quality use information based pharmacokinetic theories and the clinical studies in interaction of cardiovascular agents.
Studies on quality use information based pharmacokinetic theories and the clinical studies in interaction of cardiovascular agents.
批准号:
20590162
负责人:
UENO Kazuyuki
金额:
$1.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Drug-interactions of cardiovascular agents were studies in animal studies and clinical studies. For example、it was suggested when losartan was coadministered CYP2C9 inhibiters, the pharmacodynamics effects was decreased due to decrease of the active metabolite concentration. Quality use informations of disopiramide aprindine, pirmenol and cibenzoline were established based on the population pharmacokinetic analysis. It was considered that this information contribute the drug therapy of cardiovascular diseases.
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Pharmacokinetics of ceftriaxione, which is a third-generation cephalosporin, in pediatric patients.
头孢曲松(第三代头孢菌素)在儿科患者中的药代动力学。
DOI:
--
发表时间:
2009
期刊:
Biol Pharm Bull 32
影响因子:
--
作者:
[Kyoko Fukumoto, Shiori Aida, Tomohiro Oishi, Kazuyuki Ueno]
通讯作者:
Kazuyuki Ueno
The effect of bucolome, a CYP2C9 inhibitor, on the pharmacokinetics of losartan. Drug Metabol.
CYP2C9 抑制剂 bucolome 对氯沙坦药代动力学的影响。
DOI:
--
发表时间:
2008
期刊:
Pharmacokin. 23
影响因子:
--
作者:
[Kobayashi M, Takagi M, Fukumoto K, Kato R, Tanaka T, Ueno K]
通讯作者:
Ueno K
母集団解析に基づくジゴキシンクリアランスに及ぼす併用薬の影響度の検討
基于群体分析检查合并药物对地高辛清除率的影响
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[本間悠子, 福本恭子, 上野和行]
通讯作者:
上野和行
テイコプラニン製剤における成分含量比に関する検討
替考拉宁制剂成分含量比的研究
DOI:
--
发表时间:
2010
期刊:
医学と薬学
影响因子:
--
作者:
[上野和行, 福本恭子]
通讯作者:
福本恭子
Effects of serum concentrations of disopyramide and its metabolite mono-N-dealkyldisopyramide on the anticholinergic side effects associated with disopyramide.
丙吡胺及其代谢物单-N-脱烷基二丙吡胺的血清浓度对与丙吡胺相关的抗胆碱能副作用的影响。
DOI:
--
发表时间:
2008
期刊:
Biol.Pharm.Bull. 31
影响因子:
--
作者:
[Tsuchishita Y, Fukumoto K, Kusumoto M, Ueno K.]
通讯作者:
Ueno K.
共 29 条
Development of a magnetic suspension system for wind-tunnel models moving in two-degree of freedom
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批准号:19K04186
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2019
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负责人:UENO Kazuyuki
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依托单位:
Preliminary Investigation of Magnetic Fluid Active Damper
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批准号:09555061
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.86万
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财政年份:1997
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负责人:UENO Kazuyuki
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依托单位:
High Functionalbility of Magnetic Fluid and its Application
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批准号:09044118
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$1.79万
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财政年份:1997
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负责人:UENO Kazuyuki
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依托单位:
海外基金