Intake of Citrus Fruits associated with Atherosclerosis, Aging, and the Risk of Cardio-cerebro Vascular Disease.

柑橘类水果的摄入与动脉粥样硬化、衰老和心脑血管疾病的风险有关。

• 批准号: 20590648
• 负责人: OKADA Katsutoshi
• 金额: $ 2.91万
• 依托单位: Ehime University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20590648/
• 关键词: 果物摂取; 動脈硬化; 体力; 循環器疾患; 高次機能; 抗加齢作用

We conducted a prospective cohort study. A total of 10,000 participants living in communities, free of prior diagnosis of cardiovascular disease completed health check-up examination and food frequency questionnaire. About intake of mikan (mandarin oranges), daily intake of high season was negatively associated with risk of cardiovascular disease and mortality as was daily intake of annual average. Further we found U-shaped risk curve. Therefore we thought there were upper limit of adequate intake for mikan. In addition, when participants of 65 years old had a cognitive function comparable, if their atherosclerosis of carotid artery by ultrasound measurement were stronger, there was more decrease of those function at 5 years later. In conclusion, prevention of atherosclerosis up to 65 years oldwas important.

我们进行了一项前瞻性队列研究。共有 10,000 名居住在社区且未曾诊断出心血管疾病的参与者完成了健康体检和食物频率调查问卷。关于橘子的摄入量，旺季的每日摄入量与年平均每日摄入量呈负相关，与心血管疾病和死亡率的风险呈负相关。进一步我们发现U形风险曲线。因此我们认为蜜柑的摄入量是有上限的。此外，当65岁的参与者具有相当的认知功能时，如果超声测量的颈动脉粥样硬化程度越强，则5年后认知功能的下降越多。总之，65 岁以下人群预防动脉粥样硬化非常重要。

项目成果

Which Diagnostic Criteria of Metabolie Syndrome Can Better Predict the Risk of Ischemic Heart Disease and stroke in Japanese and Asian Populations?

哪种代谢综合征诊断标准可以更好地预测日本和亚洲人群缺血性心脏病和中风的风险？

• 发表时间: 2008
• 期刊: Hypertension Res. 31
• 作者: Momiyama Y;Okada K;et al.;Okada K;Okada K.;Okada K
• 通讯作者: Okada K

65歳の一般集団における動脈硬化度が5年後のIADL及び高次脳機能に及ぼす影響ついて

动脉硬化程度对65岁普通人群5年后IADL和较高脑功能的影响

• 发表时间: 2011
• 作者: 岡田克俊;等
• 通讯作者: 等

Hypertension without obesity and metabolic syndrome was still important for cardiovascular disease at Japanese Cohort study started in new Millennium.

在新千年开始的日本队列研究中，没有肥胖和代谢综合征的高血压对于心血管疾病仍然很重要。

• 发表时间: 2010
• 作者: Okada K;et al.
• 通讯作者: et al.

ホームページ

主页

Prognostic value of plasma high-sensitivity C-reactive protein levels in Japanese patients with stable coronary artery disease.

日本稳定型冠状动脉疾病患者血浆高敏 C 反应蛋白水平的预后价值。

• 发表时间: 2009
• 期刊: Atherosclerosis 207
• 作者: Momiyama Y;Okada K (8人中4番目);et al.
• 通讯作者: et al.