Directional control of cell polarization revealed by quantitative measurement and mathematical modeling

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Cells polarize along with the axes of the animal body. Cell polarity is maintained by dynamic equilibrium of protein movements. In this study, I succeeded to apply and develop the new systems to reveal protein dynamics quantitatively to developmental biology (Edge-detection image processing program, Fluorescence correlation spectroscopy (FCS), Total internal reflection fluorescence microscope (TIRFM)). Based on the achievements of this study, I will carry out mathematical modeling to understand cell polarization as a dynamical system.