Evolutionary conserved mechanisms of cell movements in metazoans : insights from the ctenophore Brachyury
Evolutionary conserved mechanisms of cell movements in metazoans : insights from the ctenophore Brachyury
批准号:
20770190
负责人:
YAMADA Atsuko
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Injection of RNA encoding a dominant-interfering construct of M1Bra, a Brachyury (Bra) ortholog of the ctenophore Mnemiopsis leidyi, into Xenopus embryos revealed that MlBra could regulate Xenopus gastrulation in the same way as the endogenous Xenopus Bra (Xbra), suggesting that the role of Bra in cell movements is conserved over the species. In addition, microarray analyses in Xenopus embryos suggested that Delta-Notch signaling components and the purine-nucleoside phosphorylase gene may function downstream of Bra.
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Study on ancestral roles of the Brachyury gene during metazoan evolution
Brachyury 基因在后生动物进化过程中的祖先作用研究
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Atsuko Yamada, Mark Q.Martindale, Akimasa Fukui, Hidemi Watanabe, Shin Tochinai]
通讯作者:
Shin Tochinai
Highly conserved functions of the Brachyury gene on morphogenetic movements: insight from the early-diverging phylum Ctenophora.
Brachyury 基因在形态发生运动中的高度保守功能:来自早期分化的栉水母门的见解。
DOI:
--
发表时间:
2010
期刊:
Developmental Biology
影响因子:
2.7
作者:
[A. Yamada, M. Martindale, A. Fukui, S. Tochinai]
通讯作者:
S. Tochinai
Brachyuryタンパク質の結合サイト配列を用いたBrachyury標的遺伝子の探索
使用 Brachyury 蛋白结合位点序列搜索 Brachyury 靶基因
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[山田温子, 小柳香奈子, 渡邉日出海]
通讯作者:
渡邉日出海
Highly conserved functions of the Brachyury gene on morphogenetic movements : Insight from the early-diverging phylum Cteonphora
Brachyury 基因在形态发生运动中的高度保守功能:来自早期分化的 Cteonphora 门的见解
DOI:
--
发表时间:
2010
期刊:
Developmental Biology 339
影响因子:
--
作者:
[Yamada, A, Martindale, M.Q., Fukui, A., Tochinai, S., Atsuko Yamada]
通讯作者:
Atsuko Yamada
In silico and in vivo surveys of Brachyury target gens in vertebrates
脊椎动物 Brachyury 目标基因的计算机和体内研究
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Atsuko Yamada, Kanako O.Koyanagi, Hidemi Watanabe]
通讯作者:
Hidemi Watanabe
海外基金