Identification of fresh and seawater specific molecular markers in teleosts

广盐鱼可以通过特殊的“富线粒体细胞”（MRCs）在淡水和海水中生存。尽管MRCs被认为既参与淡水中的离子吸收，也参与海水中的离子分泌，但其离子吸收机制30多年来一直存在争议。本研究在罗非鱼MRCs中发现了一种新的淡水型离子转运体，并提出了一种新的离子摄取模型。我们还发现，不同鱼类的离子摄取机制各不相同。这些发现为研究鱼类的渗透和离子调节打开了一扇新的窗口。

Euryhaline fish can live in both fresh water and seawater by means of specialized "mitochondrion-rich cells (MRCs)". Although MRCs are considered to be involved in both ion uptake in fresh water and ion secretion in seawater, the ion-uptake mechanism has been controversial for over 30 years. In this study, we identified a novel freshwater-type ion transporter in tilapia MRCs and proposed a new ion uptake model. We also found that ion uptake mechanisms vary among fish species. These findings are opening a new window for the study on fish osmo- and iono-regulation.