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Analysis of translational inhibition by basic amino acid repeat

Analysis of translational inhibition by basic amino acid repeat
碱性氨基酸重复的翻译抑制分析
批准号:
20790095
负责人:
AKIMITSU Nobuyoshi
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009

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中文摘要
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英文摘要
Bio-infomatic analysis revealed that human genome encode 267 genes which harbor basic amino acid repast. This suggests that 0.7% of all human genes are regulated by basic amino acid repast-mediated translational repression. To investigate this idea, several reporter genes encoding basic amino acid repast sequence were constructed and tested. Moreover, we found that TAT gene encoded in HIV genome also encodes basic amino acid repast. However, basic amino acid repast of TAT gene is not involved in translational repression-mediated gene regulation.
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会议论文
High-throughput screening assay of hepatitis C virus helicas e inhibitors usinc fluorescence?auenchina phenomenon
使用荧光法对丙型肝炎病毒螺旋e抑制剂进行高通量筛选?auenchina现象
DOI: --
发表时间: 2009
期刊: Biochem Biophys Res Commun. 379
影响因子: --
作者: [Tani H., Akimitsu N., Fujita O., Matsuda Y., Miyata R., Tsuneda S., Igarashi M., Sekiguchi Y., Noda N., 谷英典]
通讯作者: 谷英典
DOI: 10.1016/j.bbrc.2010.01.100
发表时间: 2010-02-26
期刊: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
影响因子: 3.1
作者: [Tani, Hidenori, Fujita, Osamu, Noda, Naohiro]
通讯作者: Noda, Naohiro
High-throughput screening assay of hepatitis C virus helicase inhibitors using fluorescence-quenching phenomenon.
利用荧光猝灭现象对丙型肝炎病毒解旋酶抑制剂进行高通量筛选测定。
DOI: --
发表时间: 2009
期刊: Biochem Biophys Res Commun. 379
影响因子: --
作者: [Tani H., Akimitsu N., Fujita O., Matsuda Y., Miyata R., Tsuneda S., Igarashi M., Sekiguchi Y., Noda N.]
通讯作者: Noda N.
Transcriptional regulation of nuclear long noncoding RNA in mammalian cells
  • 批准号:
    23790077
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.83万
  • 财政年份:
    2011
  • 负责人:
    AKIMITSU Nobuyoshi
  • 依托单位:
Functional analysis of a role of prolylendopeptidase in brain by constructing gene targeting mice
  • 批准号:
    12672105
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.05万
  • 财政年份:
    2000
  • 负责人:
    AKIMITSU Nobuyoshi
  • 依托单位:
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