Functional analysis of novel lipid-metabolizing enzymes belonging to the NlpC/p60 family
Functional analysis of novel lipid-metabolizing enzymes belonging to the NlpC/p60 family
批准号:
20790231
负责人:
UYAMA Toru
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
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英文摘要
We investigated possible lipid-metabolizing activities of HRASLS family members which were originally identified as tumor suppressor genes. H-rev107, HRASLS2 and TIG3, which are included in the HRASLS family members, showed lipid-metabolizing activities using glycerophospholipids as substrate. PCR analysis revealed that H-rev107 and TIG3 are expressed in all the tissues examined, with the highest expression of H-rev107 in adipose tissue. On the other hand, the expression of HRASLS2 was dominant in liver and kidney with low levels in other tissues.
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CHARACTERIZATION OF THE TUMOR SUPPRESSOR H-REV107 AS A NOVEL Ca^<2+>-INDEPENDENT CYTOSOLIC PHOSPHOLTPASE A_<1/2>
肿瘤抑制剂 H-REV107 作为新型 Ca^2>-独立胞质磷酸酶 A_<1/2> 的表征
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Jun Wang, et.al, 中川誠人, 中川誠人, Toru Uyama, 中川誠人, 中川誠人, Toru Uyama, 中川誠人, Toru Uyama, 中川誠人, Toru Uyama]
通讯作者:
Toru Uyama
癌抑制遺伝子H-Rev107のCa2+-非依存性ホスホリパーゼA1/A2としての解析
抑癌基因 H-Rev107 作为 Ca2+ 非依赖性磷脂酶 A1/A2 的分析
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[上田夏生, 宇山徹, 森下淳, 金星華]
通讯作者:
金星華
Expression and secretion of N-acylethanolamine-hydrolyzing acid amidase in human prostate cancer cells
N-酰基乙醇胺水解酰胺酶在人前列腺癌细胞中的表达和分泌
DOI:
--
发表时间:
2008
期刊:
J Biochem 144
影响因子:
--
作者:
[Wang J, Zhao L-Y, Uyama T, Tsuboi K, Wu X-X, Kakehi Y, Ueda N]
通讯作者:
Ueda N
cDNA cloning and characterization of human and mouse Ca^<2+>- independent nhosnhatidvlethanolamine N-acyltransferases
人和小鼠Ca^2-独立的nhosnhatidylethanolamine N-酰基转移酶的cDNA克隆和表征
DOI:
--
发表时间:
2009
期刊:
Biochimica et Biophysica Acta 1792
影响因子:
--
作者:
[Xing-Hua Jin, et.al.]
通讯作者:
et.al.
DOI:
10.1016/j.bbalip.2008.09.006
发表时间:
2009-01-01
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
影响因子:
4.8
作者:
[Jin, Xing-Hua, Uyama, Toru, Ueda, Natsuo]
通讯作者:
Ueda, Natsuo
共 27 条
Functional analysis of PLA/AT family members functioning as lipid-metabolizing enzymes
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批准号:24590355
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
-
财政年份:2012
-
负责人:UYAMA Toru
-
依托单位:
Identification of endogenous substrates for HRASLS family members and their functional analysis
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批准号:22790294
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.16万
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财政年份:2010
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负责人:UYAMA Toru
-
依托单位: