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Functional analysis of the proteins with TPR motifs which are associated with the cerebral nerve function

Functional analysis of the proteins with TPR motifs which are associated with the cerebral nerve function
与脑神经功能相关的TPR基序蛋白质的功能分析
批准号:
20790292
负责人:
IZUMIYAMA Tomohiro
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009

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中文摘要
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英文摘要
We studied about TPRBK protein which were highly expressed in human and mouse brain tissue and embryonic tissue of medaka. We carried out coimmunoprecipitation analysis to identify proteins which interact with TPRBK protein and immunofluorescence assay by using anti-TPRBK antibody. These studies revealed that : First, TPRBK interacts with X and Y which are associated with the function of cell division. Second, the localization of TPRBK is changed from centrosomes to the midbody during mitosis and cytokinesis. Third, TPRBK associates with the system of cytokinesis.
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会议论文
ヒト22番染色体由来の新規タンパクTPRBKは中心体の機能に関与している
TPRBK 是一种源自人类 22 号染色体的新型蛋白质,参与中心体功能
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Inamura K, Takeuchi K, Togashi Y, Hatano S, Ninomiya H, Motoi N, Mun MY, Sakao Y, Okumura S, Nakagawa K, Soda M, Choi YL, Mano H, Ishikawa Y., 泉山朋大]
通讯作者: 泉山朋大
ヒト22番染色体由来の新規タンパクTPRBKの性状解析:細胞分裂への関与
TPRBK(一种源自人类 22 号染色体的新型蛋白质)的表征:参与细胞分裂
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [R Hanyu, et al., 泉山朋大]
通讯作者: 泉山朋大
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