Serum biomarkers and the risk of pancreatic cancer in a prospective study

前瞻性研究中的血清生物标志物和胰腺癌风险

• 批准号: 20790450
• 负责人: LIN Yingsong
• 金额: $ 2.16万
• 依托单位: Aichi Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20790450/
• 关键词: 膵がん; 血清バイマーカー; リスク; コホート内症例対照研究; 血清マーカー

The associations of serum TGF-β1, CRR, and anti-H. pylori antibody with the risk of pancreatic cancer death were exalrlined in a nested case-control study within the Japan Collaborative Cohort Study. Elevated baseline serum TGF-β1 was associated with an increased risk of pancreatic cancer death. Serum CRP was higher among cases than among control subjects. Overall no associations were observed between H.pylori infection, serum CRP and pancreatic cancer risk.

血清转化生长因子-β-1、血肌酐和抗-H.在日本合作队列研究中的一项嵌套病例对照研究中，幽门螺杆菌抗体与胰腺癌死亡风险有关。基线血清转化生长因子-β-1升高与胰腺癌死亡风险增加相关。病例组血清C反应蛋白水平高于对照组。总体而言，没有观察到幽门螺杆菌感染、血清CRP和胰腺癌风险之间的关联。