Effect of Passive Exercise on Systemic Endothelial Function in Elderly Patients with Chronic Heart Failure

据报道，使用伺服动态控制测功器的被动腿部循环运动训练(Plet)对运动耐量严重受损的患者很有用。本研究的目的是进行一项先导性研究，并初步评估监督下的Plet对老年慢性心力衰竭(CHF)患者内皮功能的安全性和有效性。27例老年充血性心力衰竭患者被前瞻性随机分为Plet组(n=13)和对照组(n=14)。用RH-PAT指数评估，Plet组患者的内皮功能有增加的趋势(p=0.07)，但在对照组中保持不变。两组的6分钟步行距离均显著增加(P&lt；0.001)。在这项研究的监督条件下，Plet似乎耐受性良好，对老年CHF患者可能是安全的。需要更多的研究来进一步评估这种方法的安全性和潜在的好处。

Passive leg cycle exercise training (PLET) using a servo-dynamically controlled ergometer has been reported to be useful in patients with severely impaired exercise tolerance. The purpose of this study was to perform a pilot study and make a preliminary assessment of the safety and efficacy of supervised PLET on endothelial function in elderly patients with chronic heart failure (CHF). Twenty-seven elderly patients with CHF were prospectively randomized to either PLET group (n=13) or control group (n=14). Patients in the PLET group showed a trend toward increase in endothelial function assessed by RH-PAT indexes (p = 0.07), but it remained unchanged in the control group. The significant increase in 6-minute walk distance was observed in both groups (p < 0.001). PLET under the supervised conditions of this study appears to be well tolerated and may be safe for elderly patients with CHF. More research is needed to further evaluate the safety and potential benefits of this approach.