Regulation of VEGF expression by PPAR in human lung cancer cells
Regulation of VEGF expression by PPAR in human lung cancer cells
批准号:
20790562
负责人:
TANNO Sachie
金额:
$2.66万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
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英文摘要
Thiazolidinedione (TZD) use in patients with diabetes was specifically associated with reduced risk of lung cancer. Since collagen XVIII is one of the strongest predictors of outcome in patients with lung cancer, we examined the effects of TZD on expression of collagen XVIII in human non-small lung cancer (NSCLC) cells. The present results results suggest for the first time that TZDs reduced expression of collagen XVIII in NSCLC, which may help us understand the mechanism why TZDs use has chemopreventive action.
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会议论文
Thiazolidinediones enhance vascular endothelial growth factor expression and induce cell growth inhibition in non-small-cell lung cancer cells
噻唑烷二酮类增强非小细胞肺癌细胞中血管内皮生长因子的表达并诱导细胞生长抑制
DOI:
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发表时间:
2010
期刊:
J Exp Clin Cancer Res
影响因子:
--
作者:
[Yoshizaki T, Motomura W, Tanno S, Kumei S, Yoshizaki Y, Tanno S, Okumura T]
通讯作者:
Okumura T
Monitoring of Emerging Resistance of Lung Cancer using Liquid Biopsy
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批准号:15K09239
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2015
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负责人:TANNO Sachie
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依托单位:
海外基金