Effects of omentopexy combined with granulocyte colony-stimulating factor in a rabbit heart model

大网膜固定术联合粒细胞集落刺激因子对兔心脏模型的影响

• 批准号: 20790985
• 负责人: ISHIDA Narihiro
• 金额: $ 2.75万
• 依托单位: Gifu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20790985/
• 关键词: G-CSF; 大網充填; 血管新生; 心機能

We investigated whether or not omentopexy combined with granulocyte colony-stimulating factor (G-CSF) subcutaneous administration reduced infarction area and improved left ventricular (LV) dysfunction in a coronary occlusion and reperfusion model. Echocardiography showed improvement of LV dysfunction and infarction/ischemic area ratio was reduced. Omentopexy with G-CSF administration improved LV function and decreased infarction area.

在冠状动脉闭塞和再灌注模型中，我们研究网膜穿刺联合粒细胞集落刺激因子（G-CSF）皮下给药是否能减少梗死面积并改善左心室功能障碍。超声心动图显示左室功能障碍改善，梗死/缺血面积比降低。网膜固定术加G-CSF可改善左室功能，减少梗死面积。

项目成果

Reduction of infarction area and improvement of left ventricular dysfunction by omentopexy combined with granulocyte colony-stimulating factor adminidtration in a coronary occlusion and reperfusion rabbit model

大网膜固定术联合粒细胞集落刺激因子注射减少兔冠状动脉闭塞再灌注模型梗死面积并改善左心室功能障碍

• 发表时间: 2009
• 作者: Shinsuke Matsumoto;et.al.;Narihiro Ishida
• 通讯作者: Narihiro Ishida

G-CSF皮下投与大網充填術の左室機能に及ぼす影響

皮下注射 G-CSF 对左心室功能的影响

• 发表时间: 2008
• 作者: Shinsuke Matsumoto;et.al.;Narihiro Ishida;Narihiro Ishida;石田成吏洋
• 通讯作者: 石田成吏洋