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Development of human lung cancer model using NOD/SCID/γC null mouse

Development of human lung cancer model using NOD/SCID/γC null mouse
使用 NOD/SCID/γC null 小鼠建立人类肺癌模型
批准号:
20790999
负责人:
INOUE Yoshimasa
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009

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项目成果

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中文摘要
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英文摘要
We studied a noninvasive method to evaluate tumor growth in the lung of mice. Xenotransplant model of lung cancer (NSCLC) using NOD/SCID/γcnull (NOG) mice was developed by tail vain injection of human lung cancer cell line (A549). The lung consolidation detected by MRI (magnetic resonace imageing) deteriorated in parallel with intrapulmonary tumor growth. MRI may be useful to noninvasively evaluate tumor growth in lung of mice.
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