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The effect of MCP-1 on the pathogenesis of giant papillae formation of the conjunctiva in vernal keratoconjunctivitis

The effect of MCP-1 on the pathogenesis of giant papillae formation of the conjunctiva in vernal keratoconjunctivitis
MCP-1对春季角结膜炎结膜巨乳头形成的影响
批准号:
20791255
负责人:
FUJITSU Youichiro
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009

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中文摘要
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英文摘要
Vernal keratoconjunctivitis is characterized by giant papilla formation. Increased expression of MCP-1 was also reported in the conjunctiva of patients with vernal keratoconjunctivitis. Human conjunctival fibroblasts express CCR2, and MCP-1 stimulates both the proliferation of and the production of extracellular matrix proteins such as fibronectin, procollagen type I C-peptide and type III collagen, in the dose dependent manner by these cells through MAPK pathway.
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DOI: --
发表时间: 2008
期刊: Japanese journal of Ophthalmology 52
影响因子: --
作者: [Ooto S, Tsujikawa A, Mori S, Tamura H, Yamashiro K, Yoshimura N., Nobuhiko Chikamoto]
通讯作者: Nobuhiko Chikamoto
後部ぶどう腫境界部に強い牽引を生じ萎縮性円孔を多発した網膜剥離の1例
葡萄肿后缘强牵引、多发萎缩孔视网膜脱离一例。
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Tsujikawa A, Ojima Y, Yamashiro K, Ooto S, Tamura H, Nakagawa S, Yoshimura N., 藤津揚一朗]
通讯作者: 藤津揚一朗
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