Study on the role of dendritic cells in oral autoimmune diseases

为靶向诱导应用树突状细胞进行免疫治疗，或如何参与口腔鳞状细胞癌的发生、分化和增殖，识别ΔNp63正常口腔黏膜上皮干细胞标记物等方面的研究和探讨，已经展开。因此，重度异型增生提示从口腔鳞癌的易癌到ΔNp63的出现都参与了口腔鳞癌的发生，随着ΔNp63的高表达也是上皮异型增生的表现。此外，ΔNp63被认为参与口腔鳞癌细胞的分化和增殖。

For target lead to immunotherapy using dendritic cells, or how to get involved in the occurrence of oral Squamous Cell Carcinoma (OSCC), differentiation and proliferation, recognizing Δ Np63 normal oral mucosa epithelial stem cell markers in the research and study, the research has been conducted. As a result, heavy degree of epithelial dysplasia suggested that from easy-to-cancer by OSCC to Δ Np63 appearance are involved in the occurrence of OSCC are higher degrees as the expression of Δ Np63 higher was also the expression of epithelial dysplasia. In addition, was considered Δ Np63 is involved in OSCC cell differentiation and proliferation.