Measurement of pressure distribution under the denture base and observation of bone metabolic activity under denture base using NaF-PET/CT in vivo

NaF-PET/CT活体测量义齿基托下压力分布及观察义齿基托下骨代谢活性

• 批准号: 20890021
• 负责人: SUENAGA Hanako
• 金额: $ 2.1万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (Start-up)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20890021/
• 关键词: 義歯床下圧力動態; 生体内測定; NaF-PET; 骨代謝定量; ヒト; PET

To examine how denture insertion influenced the bone metabolism at the residual ridge beneath the denture base, Fluorine-18 NaF positron-emission tomography (NaF-PET) and X-ray computed tomography (CT) images were taken 0 day, 1 week, 6 weeks and 13 weeks after delivery of the removable partial denture (RPD). X-ray CT images showed no obvious change of bone structure beneath RPD with time after delivery of the RPD, and CT value at bone beneath RPD did not change. However, PET standardized uptake value at bone beneath RPD gradually increased after RPD delivery despite no clinical complications in the denture-supporting tissues, such as pain and inflammation. This result showed that wearing of the denture increase the bone turn over beneath the denture base gradually without the change of bone structure and volume.

为了研究义齿植入对义齿基托下残脊骨代谢的影响，我们在植入可摘局部义齿（RPD）后第0天、第1周、第6周和第13周分别拍摄了氟-18 NaF正电子发射断层扫描（NaF- pet）和x线计算机断层扫描（CT）。RPD分娩后，x线CT图像显示RPD下骨结构随时间无明显变化，RPD下骨CT值无变化。然而，在RPD分娩后，尽管义齿支持组织没有出现疼痛和炎症等临床并发症，但RPD下骨的PET标准化摄取值逐渐增加。结果表明，佩戴义齿后，义齿基托下骨周转率逐渐增加，但骨结构和骨体积没有变化。

项目成果

Development of in vivo measuring system of the pressure distribution under the denture base of removable partial denture

• DOI: 10.1016/j.jpor.2008.08.006
• 发表时间: 2009-01-01
• 期刊: JOURNAL OF PROSTHODONTIC RESEARCH
• 影响因子: 3.6
• 作者: Kubo, Kei;Kawata, Tetsuo;Sasaki, Keiichi
• 通讯作者: Sasaki, Keiichi

Development of in vivo measuring system of the pressure distribution under the denture base of removable partial dendure

可摘局部义齿基托下压力分布体内测量系统的研制

• 发表时间: 2009
• 期刊: J Prosthodontic Res. 53
• 作者: K Kubo;T Kawata;H Suenaga;N Yoda;R Shigemitsu;T Ogawa;K Sasaki
• 通讯作者: K Sasaki