Measurement of pressure distribution under the denture base and observation of bone metabolic activity under denture base using NaF-PET/CT in vivo

为了解义齿植入对义齿基托下残留牙槽骨骨代谢的影响，分别于义齿植入后0d、1周、6周和13周进行18NaF正电子发射断层扫描(NAF-PET)和X线计算机断层扫描(CT)检查。X线片显示RPD下的骨结构随时间变化不明显，CT值也无明显变化。然而，尽管义齿支持组织没有出现疼痛和炎症等临床并发症，但在RPD交付后，RPD下骨处的PET标准化摄取值逐渐增加。这一结果表明，义齿佩戴后，义齿基托下的骨翻转率逐渐增加，而骨的结构和体积没有发生变化。

To examine how denture insertion influenced the bone metabolism at the residual ridge beneath the denture base, Fluorine-18 NaF positron-emission tomography (NaF-PET) and X-ray computed tomography (CT) images were taken 0 day, 1 week, 6 weeks and 13 weeks after delivery of the removable partial denture (RPD). X-ray CT images showed no obvious change of bone structure beneath RPD with time after delivery of the RPD, and CT value at bone beneath RPD did not change. However, PET standardized uptake value at bone beneath RPD gradually increased after RPD delivery despite no clinical complications in the denture-supporting tissues, such as pain and inflammation. This result showed that wearing of the denture increase the bone turn over beneath the denture base gradually without the change of bone structure and volume.