Measurement of pressure distribution under the denture base and observation of bone metabolic activity under denture base using NaF-PET/CT in vivo

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To examine how denture insertion influenced the bone metabolism at the residual ridge beneath the denture base, Fluorine-18 NaF positron-emission tomography (NaF-PET) and X-ray computed tomography (CT) images were taken 0 day, 1 week, 6 weeks and 13 weeks after delivery of the removable partial denture (RPD). X-ray CT images showed no obvious change of bone structure beneath RPD with time after delivery of the RPD, and CT value at bone beneath RPD did not change. However, PET standardized uptake value at bone beneath RPD gradually increased after RPD delivery despite no clinical complications in the denture-supporting tissues, such as pain and inflammation. This result showed that wearing of the denture increase the bone turn over beneath the denture base gradually without the change of bone structure and volume.