Identification and characterization of a new factor regulating SREBP-1c gene in liver.
Identification and characterization of a new factor regulating SREBP-1c gene in liver.
批准号:
20591058
负责人:
NISHIO Yoshihiko
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
We have shown that RBMX and its binding protein SAFB regulate the transcriptional activity of SREBP-1c gene. Furthermore, we have identified a new gene, hepothetical protein LOC 673353, really expressing as mRNA and protein regulating SREBP-1c gene.
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SAFB1, an RBMX-Binding Protein, is a Newly Identified Regulator of Hepatic SREBP-lc Gene
SAFB1 是一种 RBMX 结合蛋白,是新鉴定的肝脏 SREBP-lc 基因的调节因子
DOI:
--
发表时间:
期刊:
BMB reports (In press)
影响因子:
--
作者:
[Omura Y, Nishio Y, Takemoto T, Ikeuchi C, Sekine O, Maeno Y, Obata T, Ugi S, Maegawa H, Kimura H, Kashiwagi A]
通讯作者:
Kashiwagi A
Postprandial activation of protein kinase Cm regulates the expression of adipocytokines via the transcription factor AP-2b.
餐后蛋白激酶 Cm 的激活通过转录因子 AP-2b 调节脂肪细胞因子的表达。
DOI:
--
发表时间:
2011
期刊:
Int J Mol Med.PubMed 28(1)
影响因子:
--
作者:
[Kondo M, Ugi S, Morino K, Fuke T, Obata T, Yoshizaki T, Nishio Y, Maeda S, Kashiwagi A, Maegawa H.]
通讯作者:
Maegawa H.
A Newly Identified Protein, LOC673353, Activates the Promoter of SREBP-1c Gene through Direct Binding to Its Promoter and Association with a Co-Activator, RBMX.
新鉴定的蛋白质 LOC673353 通过直接结合 SREBP-1c 基因的启动子并与辅激活剂 RBMX 关联来激活 SREBP-1c 基因的启动子。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Sekine O, Nishio Y, Ikeuchi C, Takemoto T, Quynh N, Ugi S, Maegawa H, Kimura H, Kashiwagi A]
通讯作者:
Kashiwagi A
Postprandial activation of protein kinase Cツオ regulates the expression of adipocytokines via the transcription factor AP-2beta
餐后蛋白激酶 C2 激活通过转录因子 AP-2beta 调节脂肪细胞因子的表达
DOI:
--
发表时间:
2011
期刊:
Int J Mol Med
影响因子:
5.4
作者:
[Kondo M, Ugi S, Morino K, Fuke T, Obata T, Yoshizaki2T, Nishio Y, Maeda S, Kashiwagi A, Maegawa H]
通讯作者:
Maegawa H
Transcription factor activating protein-2beta : a positive regulator of monocyte chemoattractant protein-1 gene expression.
转录因子激活蛋白-2β:单核细胞趋化蛋白-1 基因表达的正调节因子。
DOI:
--
发表时间:
2009
期刊:
Endocrinology. 150(4)
影响因子:
--
作者:
[Kondo M, Maegawa H, Obata T, Ugi S, Ikeda K, Morino K, Nakai Y, Nishio Y, Maeda S, Kashiwagi A.]
通讯作者:
Kashiwagi A.
共 24 条
The effects of omega-3 PUFA on vascular function
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批准号:23591336
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2011
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负责人:NISHIO Yoshihiko
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依托单位:
Elucidation of the mechanism for the activation of transcription factors and gene response in the aorta of the Postprandial state of rata
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批准号:18590981
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.51万
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财政年份:2006
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负责人:NISHIO Yoshihiko
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依托单位:
Identification of the inhibitory factor for the transcription of inflammatory genes in vascular smooth muscle cells
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批准号:16590877
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2004
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负责人:NISHIO Yoshihiko
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依托单位:
A novel effect of insulin on vascular smooth muscle cells through the transcriptional regulation ?the meaning of the activation of C/EBP
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批准号:14571090
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2002
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负责人:NISHIO Yoshihiko
-
依托单位:
Identification of oxidative stress related genes and transcription factors in vascular tissues
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批准号:11671112
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:1999
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负责人:NISHIO Yoshihiko
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依托单位:
海外基金