Brain structural change in child and adolescent depression

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Depression is a major mental health problem in child and adolescent and the prevalence is estimated approximately 5-8% and is gradually increased. However, there is no biological maker for child and adolescent for diagnosis and treatment. To find association between biomarkers and symptoms for child depression is important. 8 major depressive disorder child and age matched non-depressive 7clinical samples are participated in an MRI experiment. Whole-brain analyses were conducted and the results of these analyses were examined for potential relationships with depression severity, Quality of life and General psychopathology.