Susceptibility-weighted MR imaging in misery perfusion in patients with ischemic cerebrovascular disease: comparison with 15O PET

在通过15O PET检测到的37名患有痛苦灌注的患者中的30名中，磁敏感加权MR成像显示在狭窄闭塞病变的同侧浅表和深部大脑静脉内显着的低信号。通过15O PET检测到的24名无痛苦灌注的患者中，没有一人在脑静脉内显示出显着的低信号。磁敏感加权成像在显着低信号脑静脉的可视化和脱氧血红蛋白浓度增加方面优于 GRE-EPI。我们的结果表明，磁敏感加权成像有助于识别慢性脑血管疾病的灌注痛苦。在GRE-EPI上，由于急性栓塞闭塞而导致的梗死，同侧经常可见浅表和深部大脑静脉充血。

In 30 of the 37 patients with misery perfusion detected by ^<15>O PET, susceptibility-weighted MR imaging demonstrated prominently hypointense signal within the superficial and deep cerebral veins ipsilaterally in steno-occlusive lesions. None of the 24 patients without misery perfusion detected by ^<15>O PET showed prominently hypointense signal within the cerebral veins. Susceptibility-weighted imaging was superior to GRE-EPI for visualization of the prominently hypointense cerebral veins with increased deoxyhemoglobin concentration. Our results suggest that susceptibility-weighted imaging is helpful in identifying misery perfusion in chronic cerebrovascular disease.On GRE-EPI, engorgement of superficial and deep cerebral veins was frequently seen ipsilaterally in evolving infarction due to acute embolic occlusion.