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The local gene transfer for prevention of thrombosis after percutaneous transluminal angioplasty.

The local gene transfer for prevention of thrombosis after percutaneous transluminal angioplasty.
用于预防经皮腔内血管成形术后血栓形成的局部基因转移。
批准号:
20591481
负责人:
TAMURA Syozo
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
Anticoagulation is the usual treatment for prevention of thrombosis after percutaneous transluminal angioplasty. But excessive or spontaneous bleeding may be a side effect of anticoagulation. The present study examines whether local gene transfer suppress platelet aggregation and thrombus formation after adenovirus-mediated gene transfer to injured arterial wall. Conclusion ; the local gene transfer to injured arterial wall might prevent thrombosis.
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