Usefullness of novel boronated porphyrins for both BNCT and PDT

在硼化的卟啉中，我们在术前的初始手术中将其作为PDD使用，并作为术中照射进行PDT，从而能够测量单个患者肿瘤的硼含量。因此，当我们在手术后进行BNCT时，可以使用这个实际值来判断适应症和剂量评估，这是一个优势。由于硼化的卟啉对肿瘤的能见度很高，对肿瘤有很高的蓄积性，这种化合物在光动力疗法和BNCT中都可以看到治疗的效果。

In the boronated porphyrin, we give it as a PDD use at initial surgery in preoperation and perform PDT as intraoperative irradiation and would be able to measure the boron contents of the tumor in the individual patient. An advantage to be able to use this actual value in a judgment of indication, dose assessment was, thereby, thought about when we performed BNCT following surgery. Because the boronated porphyrin is full of visibility and shows high accumulation for the tumor, this compound can expect effect of treatment in the both PDT and BNCT.