A fundamental study for the degeneration site of Bell's palsy

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HSV-1 infected to the geniculate ganglion, the root entry zone, facial nucleus in the HSV-1 primary infected mouse facial palsy model. Therefore, these three sites are thought as HSV-1 latency sites. Moreover, HSV replicated in the neuron of the the geniculate ganglion and facial nucleus in the HSV-1 reactivated mouse facial palsy model. These facts suggested that the nerve degenelation at these two sites may occur the facial palsy with HSV-1 reactivation.