A fundamental study for the degeneration site of Bell's palsy

HSV-1原发感染小鼠面神经麻痹模型中，HSV-1感染膝状神经节、面神经根进入区、面神经核。因此，这三个站点被认为是HSV-1潜伏期站点。此外，在HSV-1重新激活的小鼠面神经麻痹模型中，HSV在膝状神经节和面神经核的神经元中复制。提示这两个部位的神经退行性变可能发生HSV-1激活的面瘫。

HSV-1 infected to the geniculate ganglion, the root entry zone, facial nucleus in the HSV-1 primary infected mouse facial palsy model. Therefore, these three sites are thought as HSV-1 latency sites. Moreover, HSV replicated in the neuron of the the geniculate ganglion and facial nucleus in the HSV-1 reactivated mouse facial palsy model. These facts suggested that the nerve degenelation at these two sites may occur the facial palsy with HSV-1 reactivation.