Development of bone graft material recycling extracted teeth

摘要：恢复少量骨再生对牙周及牙槽骨的修复具有重要的临床意义。本研究将拔除的牙齿作为骨充填材料进行再利用。在本实验动物研究中，将大鼠切牙拔除后磨碎，并与羟丙基纤维素混合作为基材。将该材料注入拔牙槽内，修复腕骨临界大小的缺损处。基于显微CT的骨形态计量学和组织学观察分析表明，该材料作为骨再生核心，表明磨牙是可行的。

Abstract : It is clinically important for periodontal and alveolar ridge to regain small amount of bone regeneration. This study focused on extracted teeth which used is discarded to reuse as a bone filling material. In this experimental animal study rat incisor was milled after extraction, and mixed with hydroxyl propyl cellulose as a base material. This material was injected to the extraction socket and critical sized defect on carvalial bone. Analyses of micro CT based bone morphometry and histological observation revealed that this material served as bone regeneration core, suggesting an availability of the milled tooth.