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A study on the effects of perilla essential oil on antibacterial effectiveness and the changes in skin moisture retention in nursing care

紫苏精油抗菌效果及护理中皮肤保湿变化的研究

基本信息

批准号：
20592512
负责人：
MORIMOTO Michiko
金额：
$ 2.75万
依托单位：
University of Hyogo (2010)Yamanashi Prefectural University (2008-2009)
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2008
资助国家：
日本
起止时间：
2008 至 2010
项目状态：
已结题

项目摘要

We extracted the essential oils from natural perilla leaves and compared the bactericidal effect of these oils against methicillin-resistant Staphylococcus aureus(MRSA) with those of a commercial product made from the same oils. We added MRSA to the perilla essential oils and examined the bactericidal effectiveness. Both showed bactericidal effectiveness against MRSA within 15 to 30 minutes. The results indicated that the activity against MRSA depended on the reaction time and oil concentration. We then performed experiments with human subjects who soaked their feet and hands in foot baths and hand baths, respectively, containing perilla essential oils and examined the differences in skin moisture retention, antibacterial effectiveness, and relaxation effectiveness in this group with those in a control group. The results showed that the number of general bacteria on the skin after soaking in the hand bath and foot bath were decreased in the perilla essential oil group. After soaking, the skin moisture at the top of the hands and feet increased immediately in the perilla essential oil group compared with the control group. In addition, systolic blood pressure was signifcantly lower in the perilla essential oil group than in the control group. These results showed that the tested product increased skin moisture retention at the top of the hands and feet, lowered bacterial counts, and had effects on relaxation by lowering systolic blood pressure(foot bath), pulse(hand bath), and psychological test(POMS).

我们从天然紫苏叶中提取精油，并将这些油对耐甲氧西林金黄色葡萄球菌（MRSA）的杀菌效果与由相同油制成的商业产品进行比较。我们将 MRSA 添加到紫苏精油中并检查其杀菌效果。两者均在 15 至 30 分钟内显示出针对 MRSA 的杀菌效果。结果表明，抗MRSA的活性取决于反应时间和油浓度。然后，我们对人类受试者进行了实验，将他们的脚和手分别浸泡在含有紫苏精油的足浴和手浴中，并检查该组与对照组的皮肤保湿性、抗菌效果和放松效果的差异。结果显示，紫苏精油组浸泡手浴和足浴后皮肤上的一般细菌数量有所减少。浸泡后，与对照组相比，紫苏精油组的手脚顶部皮肤水分立即增加。此外，紫苏精油组的收缩压显着低于对照组。结果表明，受试产品增加了手脚顶部皮肤的保湿度，降低了细菌数量，并通过降低收缩压（足浴）、脉搏（手浴）和心理测试（POMS）达到放松效果。