Reconstruction of Metabolic Network for Extracting Design Principles of Natural Products

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It is necessary for the design of a natural compound to extract design information recorded in the structure of the compound, and to build a design frame based on a systematic reconstruction of metabolic network. We examined the way to express natural compounds, to reconstruct metabolic network information, and to analyze the metabolic network. The systematic way to represent compounds proposed in this study resulted in better reflecting biosynthetic information than conventional methods, which could propose the design route for any natural compound.