Control of photosensitization system by metal nanoparticles responsive to external environment

研究了金属纳米粒子表面糖识别控制的光敏化作用。在碱性介质中，将硼酸修饰的光敏剂引入到糖保护的金属纳米颗粒中。在金属纳米粒子与光敏剂络合物的荧光光谱中，观察到新的发射带。当配合物中加入葡萄糖等糖类物质时，荧光光谱发生明显变化。这意味着光敏剂通过sacchrides的相互作用从金属纳米颗粒的表面解离。因此，金属纳米颗粒-光敏剂复合物的光学性质能够通过颗粒表面的分子识别来控制。

The photosensitization controlled by saccharide recognition on the metal nanoparticles was investigated. The boronic acid appended photosensitizers were introduced into the sugar-protected metal nanoparticles in the basic medium. In fluorescence spectra of the metal nanoparticles complex with the photosensitizers, the new emission bands were observed. When sacchrides such as glucose were added to the complex, the fluorescence spectra were changed remarkably. This means that the photosensitizers are dissociated from the surface of the metal nanoparticles with the interaction of sacchrides. Therefore, the optical properties of the metal nanoparticles-photosensitizers complexes are capable of control by molecular recognition on surface of particles.