Development of the new mutagenicity evaluation technique using the transgenic mouse introduced the fluorescence protein gene

利用引入荧光蛋白基因的转基因小鼠开发新的致突变性评估技术

• 批准号: 21510037
• 负责人: HISAMATSU Shin
• 金额: $ 2.41万
• 依托单位: Azabu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21510037/
• 关键词: 影響評価手法; 変異原試験法; 遺伝子工学; 蛍光タンパク質; マウス; 蛍光タンパク質遺伝子

In order to assay for mutagenicity test against mammal, we have attempted to assemble some constructs that used target sequence for mutagenesis and fluorescence protein gene. As a result, since the plasmid that connected the sequence for detection of mutation and a fluorescence protein gene was obtained, the construct is introduced into a mouse now.

为了进行哺乳动物的致突变性试验，我们尝试组装了一些使用诱变靶序列和荧光蛋白基因的构建体。结果，由于获得了连接突变检测用序列和荧光蛋白基因的质粒，因此现在将该构建体导入小鼠。