Application of Multi-PK antibody that detects a wide variety of protein kinases

我们尝试将多PK抗体应用于各种蛋白激酶的分析。通过使用多蛋白激酶抗体对蛋白激酶进行表达筛选，我们从蘑菇、植物和斑马鱼中获得了各种新的蛋白激酶，并对其进行了鉴定。我们还开发了一种新的技术来使用多PK抗体来识别蛋白激酶，并确定了一种与糖尿病糖毒性有关的蛋白激酶。我们目前的研究表明，多PK抗体可以作为分析各种蛋白激酶的有用工具。

We attempted to apply the Multi-PK antibodies for the analysis of various protein kinases. By expression screening of protein kinases using the Multi-PK antibodies, we obtained various novel protein kinases from mushroom, plant, and zebrafish, and characterized them. We also developed a new technology to identify protein kinases using the Multi-PK antibodies, and identified a protein kinase responsible for glucotoxicity in diabetis. Our present study revealed that the Multi-PK antibodies can be used as the useful tools for the analysis of various protein kinases.