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Development of novel drug screening process by using Drosophila disease models and silk worm Cypovirus function

Development of novel drug screening process by using Drosophila disease models and silk worm Cypovirus function
利用果蝇疾病模型和蚕Cypovirus功能开发新的药物筛选方法
批准号:
21580067
负责人:
YAMAGUCHI Masamitsu
金额:
$3.16万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
β-sarcoglycan contains EGF-like amino acid sequences in its extracellular domain. In vitro analyses demonstrated thatβ-sarcoglycan can interacts with EGFR via this extracellular domain. Double mutant for Syntrophin1and2has been established. Analyses with this double mutant clarified in vivo roles of these two genes. Recombinantβ-sarcoglycan tagged with Cypovirus VP3has been successfully expressed in cultured Drosophila cells.
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会议论文
Characterization of a novel C-type lectin cDNA, CLEM20cDNA, specifically expressed in mouthparts of the flesh fly Sarcopahaga peregrina
一种新型 C 型凝集素 cDNA CLEM20cDNA 的表征,该 cDNA 在肉蝇 Sarcopahaga peregrina 的口器中特异性表达
DOI: --
发表时间: 2011
期刊: J. Insect Biotech. Sericol
影响因子: --
作者: [Yamamoto-Kihara, M., Kotani, E., Mori, H.]
通讯作者: H.
Rapid and accurate method for isolation of recombinant baculovirus with an expanded host range
快速准确分离宿主范围扩大的重组杆状病毒的方法
DOI: --
发表时间: 2010
期刊: J. Biosci. Bioeng
影响因子: --
作者: [Watanabe S, Ohta M, Kokuho T, Mori H, Inumaru S.]
通讯作者: Inumaru S.
DOI: 10.1016/j.biomaterials.2009.04.046
发表时间: 2009-09-01
期刊: BIOMATERIALS
影响因子: 14
作者: [Ijiri, Hiroshi, Coulibaly, Fasseli, Mori, Hajime]
通讯作者: Mori, Hajime
DOI: 10.1007/s11010-011-0743-3
发表时间: 2011-02
期刊: Molecular and Cellular Biochemistry
影响因子: 4.3
作者: [N. Anh;Maiko Nishitani;S. Harada;M. Yamaguchi;K. Kamei]
通讯作者: N. Anh;Maiko Nishitani;S. Harada;M. Yamaguchi;K. Kamei
37
    Genome wide search for target genes of Drosophila histone methyl transferase dG9a
    • 批准号:
      24570211
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.58万
    • 财政年份:
      2012
    • 负责人:
      YAMAGUCHI Masamitsu
    • 依托单位:
    Regulation mechanism of cell cycle by differentiation signals
    • 批准号:
      13043058
    • 项目类别:
      Grant-in-Aid for Scientific Research on Priority Areas
    • 资助金额:
      $43.65万
    • 财政年份:
      2001
    • 负责人:
      YAMAGUCHI Masamitsu
    • 依托单位:
    Comprehensive studies on establishment of transgenic flies carrying human cancer-related gene for searching anti-cancer drugs and its molecular targets
    ANALYSES OF THE TRANSCRIPTIONAL REGULATORY NETWORK FOR DROSOPHILA DNA REPLICATION GENES
    • 批准号:
      11480217
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $6.02万
    • 财政年份:
      1999
    • 负责人:
      YAMAGUCHI Masamitsu
    • 依托单位:
    海外基金