Does TOR related factors control the cell division mode and the morphogenesis in developing embryo?

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We isolated the RagGTPase family genes and mapped their spatial and temporal expression pattern in the developing embryo. We also analyzed the effects of the gene defects such as gene deletion or the translation blockage on the cell division mode in the developing embryo. The expression of two RagGTPase genes showed unique pattern, and the expression ratio of these two genes were drastically changed in the developing stage. This ratio changing of two genes suggested to switch the two cell division modes during the embryonic development. The one is a rapid cell division mode in nutrient-rich condition (early embryonic cell division with sufficient york), and another is slow cell division mode in nutrient-poor condition (late embryonic cell division or starved animal).