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Signal transduction of TLR by STM/Hrs

Signal transduction of TLR by STM/Hrs
STM/Hrs 的 TLR 信号转导
批准号:
21590527
负责人:
MURATA Kazuko
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
We investigated the effects of STAM1/2 on innate immunity, in particular, on the degradation of Toll-like receptor(TLR) family members TLR4.STAMs may play an important role in the lysosomal degradation and translocation of TLR4 upon stimulation with LPS. These observations suggest that STAMs function as negative regulators of innate immunity mediated by TLR4.
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会议论文
STAM1/2 regulate the innate immunity through TLR4 and TLR9 signaling
STAM1/2 通过 TLR4 和 TLR9 信号传导调节先天免疫
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Toyoshima, M., et. al., 井草龍太郎]
通讯作者: 井草龍太郎
Regulation of APC function by STAM1/2.
  • 批准号:
    19590488
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.91万
  • 财政年份:
    2007
  • 负责人:
    MURATA Kazuko
  • 依托单位:
Development of therapy method target against OX40 signal for allergy or autoimmune diseases
  • 批准号:
    17607001
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.3万
  • 财政年份:
    2005
  • 负责人:
    MURATA Kazuko
  • 依托单位:
海外基金