The relationship between the diagonal earlobe crease and the cardiovascular disease

耳垂斜纹与心血管疾病的关系

• 批准号: 21590900
• 负责人: HIGUCHI Yoshihiro
• 金额: $ 3万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21590900/
• 关键词: 耳朶線条; 動脈硬化; 頸動脈プラーク; 光学3次元皮膚計測装置; 皮膚老化; 光学3次元皮膚計測; 頸動脈超音波; プラークスコア; 患者対照研究; 内膜中膜肥厚; プラークナンバー

The presence of earlobe creases(ELC) has been proposed to be a marker of atherosclerosis. However, the usefulness of the degree of ELC in predicting extent of atherosclerosis has not been fully understood. The aim of the present study was to evaluate the relationship between the depth of ELC and the extent of carotid atherosclerosis. In order to determine the average largest depth of ELC, an optical analysis with the fringe projection technique was performed directly on the bilateral ELC. A stepwise multivariate regression analysis revealed that carotid plaque score(PS) demonstrated a significant independent association with the bilateral ELC depth. These findings may indicate the usefulness of the ELC depth in predicting the extent of carotid atherosclerosis, especially the carotid plaque burden as estimated by the PS.

耳垂折痕（ELC）的存在被认为是动脉粥样硬化的标志。然而，ELC程度在预测动脉粥样硬化程度方面的有用性尚未完全了解。本研究的目的是评估ELC深度与颈动脉粥样硬化程度之间的关系。为了确定ELC的平均最大深度，直接在双侧ELC上使用条纹投影技术进行光学分析。多元逐步回归分析显示，颈动脉斑块评分（PS）与双侧ELC深度有显著的独立相关性。这些发现可能表明ELC深度在预测颈动脉粥样硬化程度，特别是PS估计的颈动脉斑块负荷方面是有用的。