The effects of hydrogen gas breathing on the lung injury induced by hyperoxia
The effects of hydrogen gas breathing on the lung injury induced by hyperoxia
批准号:
21591002
负责人:
KOBAYASHI Hirosuke
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
Survival time of mice exposed to hyperoxia became longer when the mice breathed hydrogen gas, and the leukocytes accumulation in the lungs was reduced. Hydrogen gas protected cultured human alveolar epithelial cells against antimycin A-induced oxidative stress. The level of superoxide produced by mitochondria was significantly low, and the increase in superoxide produced by antimycin A was also lower in the presence of hydrogen gas. Hydrogen gas protected lungs against hyperoxic lung injury.
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DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Tomohiro Sawa, Hideshi Ihara and Takaaki Akaike, 桑野和善, 谷本圭司, Kobayashi H]
通讯作者:
Kobayashi H
DOI:
10.1016/j.imlet.2012.02.013
发表时间:
2012-05-30
期刊:
IMMUNOLOGY LETTERS
影响因子:
4.4
作者:
[Eshima, Koji, Chiba, Sayuri, Shinohara, Nobukata]
通讯作者:
Shinohara, Nobukata
Differentiation of side population cells isolated from human amniotic mesenchymal cell into vascular endothelial cells under hypoxic condition
人羊膜间充质细胞侧群细胞缺氧条件下向血管内皮细胞的分化
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Maruyama N, Nishikubo Y, Kokubo K, Shinbo T, Hirose M, Kobayashi M, Sakuragawa N, Kobayashi H]
通讯作者:
Kobayashi H
虚血再潅流障害軽減用治療剤および治療装置
减轻缺血再灌注损伤的治疗剂及装置
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[]
通讯作者:
Respiratory Rhythms in Healthy Subjects and Patients
健康受试者和患者的呼吸节律
DOI:
--
发表时间:
2010
期刊:
Advances in Experimental Medicine & Biology
影响因子:
--
作者:
[Shimane M, Tomita Y, Shinbo T, Kokubo K, Hirose M, Hataishi R, Kubota M, Masuda N, Kobayashi H]
通讯作者:
Kobayashi H
共 10 条
Ameliorating effects of nitric oxide and/or hydrogen gas inhalation on ARDS
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批准号:25461166
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2013
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负责人:KOBAYASHI Hirosuke
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依托单位:
Relationship between Topoisomerase I gene mutation in patients with lung cancer and the effect of irinotecan hydrochloride
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批准号:15590826
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:2003
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负责人:KOBAYASHI Hirosuke
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依托单位:
海外基金