Association with permeation and metastasis of colon cancer and the hyaluronic acid ～For recurrent zero of colon cancer～

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The accumulation of data was carried out by an effect of ME by confirmation and a visible bottom.Besides, it was recognized that we relatively reduced the cell adhesion ability and migration ability by reducing the hyaluronic acid production of the cancer cell.Also, the toxicity at the colon cancer cells level was confirmed indirectly.Because that the effect on extracellular matrix of ME was not a little found was inferred, we performed the digitization with the microscope to visualize a thing and adhesive property to observe the cells activity including relations with the degree and level.