Association with permeation and metastasis of colon cancer and the hyaluronic acid ～For recurrent zero of colon cancer～

数据的积累是通过确认和可见底部的ME效应进行的。此外，我们通过减少癌细胞的透明质酸产生，相对降低了细胞的粘附能力和迁移能力。在结肠癌细胞水平上的毒性也得到了间接证实。由于推测ME对细胞外基质的影响不小，因此我们用显微镜对其进行了数字化可视化和粘附性观察，观察细胞活性及其与程度和水平的关系。

The accumulation of data was carried out by an effect of ME by confirmation and a visible bottom.Besides, it was recognized that we relatively reduced the cell adhesion ability and migration ability by reducing the hyaluronic acid production of the cancer cell.Also, the toxicity at the colon cancer cells level was confirmed indirectly.Because that the effect on extracellular matrix of ME was not a little found was inferred, we performed the digitization with the microscope to visualize a thing and adhesive property to observe the cells activity including relations with the degree and level.