Selective induction and transplantation of iPS cell-derived astrocytes into acute spinal cord injury

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We transplanted iPS cell-derived astrocytes into rat spinal cords three and seven days after spinal cord contusion injury. BBB locomotor recovery did not show statistically significant change in both transplantations. Although transplanted cells were survived eight weeks after transplantation, they did not show immunoreactivity for GFAP. There was no statistical significant histological finding. Although transplanted astrocytes has relation to induce allodynia, it depends on the timing of transplantation.