Clinical research on optimal airway and respiratory managements for obese patients with obstructive sleep apnea

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1) Postural change from supine to sitting significantly improved collapsibility of pharyngeal airway in anesthetized and paralyzed patients with obstructive sleep apnea. The influences of sitting position on retropalatal airway collapsibility were smaller in patients with more severe obstructive sleep apnea. 2) Muscle paralysis, per se, under general anesthesia did not deteriorate mask ventilation in anesthetized persons, and instead, succinylcholine-induced fasciculation significantly improved mask ventilation particularly through the oral airway route. In obese patients with obstructive sleep apnea, use of the oral airway route and sitting posture are advantageous for mask ventilation.