Rhythm formation of fetal brain function and effect of maternal environmental stress

根据对胎心率模式的观察，区分出两种不同的脑功能状态。这两种不同的状态相继出现，并有一定的节奏循环。这一现象被认为代表了胎儿大脑功能的变化。我们发现，正常发育的胎儿在妊娠33周时达到节律周期，而宫内生长受限的胎儿则显着推迟了这一周期。1)大脑中动脉血流速度在活动期明显大于非活动期(图3)。2)完成了143个胎儿的节律形成测试，并将在3岁时完成发育心理学检查。

Based on the observation of fetal heart rate pattern, two different states of brain functions are differentiated. These 2 different states appear one after another with some rhythmic cycle. This phenomenon is considered to represent the functional changes of the fetal brain.We have revealed that normally developing fetus obtains the rhythmic cycle at 33 weeks of gestation whereas the intrauterine growth restricted fetus delays it significantly.(fig. 1)The middle cerebral artery Doppler velocimetry during active state varies more than that of during non active state significantly.(fig. 2)We finished the tests of rhythm formation on 143 fetuses and will completed the developmental psychological examination at the age of 3.