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Role of matrix proteins on the differentiation and activity of hard tissue forming cells and calcification during tooth formation.

Role of matrix proteins on the differentiation and activity of hard tissue forming cells and calcification during tooth formation.
基质蛋白对牙齿形成过程中硬组织形成细胞的分化和活性以及钙化的作用。
批准号:
21592329
负责人:
UCHIDA Takashi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
This study clarified that ameloblastin, one of the enamel matrix protein, suppressed mitotic activity and raised expression of amelogenin and enamelin of the ameloblat-linage cell in vitro, and was essential for normal mitosis and differentiation of cells of Hertwig' s epithelial root sheath during root formation in vivo. Moreover, ameloblastin is supposed to be one of the candidate molecules of inducing differentiation of odontoblasts and cementocytes.
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会议论文
Histological and immunohistochemical analyses of molar tooth germ in enamelin-deficient mouse.
釉质缺陷小鼠磨牙牙胚的组织学和免疫组织化学分析。
DOI: --
发表时间: 2011
期刊: Acta Histochemica
影响因子: 2.5
作者: [T. Sawada, H. Sekiguchi, T. Uchida, H. Yamashita, S. Shintani, T. Yanagisawa]
通讯作者: T. Yanagisawa
DOI: --
发表时间: 2012
期刊: Cell Tissue Res.
影响因子: --
作者: [Sasagawa I., Yokosuka H., Ishiyama M., Mikami M., Shimokawa H. Uchida T.]
通讯作者: Shimokawa H. Uchida T.
Ameloblastin regulates osteogenic differentiation by inhibiting Src kinase via cross talk between integrin beta1 and CD63.
成釉细胞通过整合素 beta1 和 CD63 之间的串扰抑制 Src 激酶,从而调节成骨分化。
DOI: --
发表时间: 2011
期刊: Mol Cell Biol
影响因子: 5.3
作者: [Iizuka S, et al.]
通讯作者: et al.
Ameloblastin regulates osteogenicdifferentiation by inhibiting Src kinasevia cross talk between integrin beta1 andCD63.
成釉素通过整合素 beta1 和 CD63 之间的串扰抑制 Src 激酶,从而调节成骨分化。
DOI: --
发表时间: 2011
期刊: Mol Cell Biol
影响因子: 5.3
作者: [Iizuka S., Kudo Y., Yoshida M., Tsunematsu T., Yoshiko Y., Uchida T., Ogawa I., Miyauchi M., Takata T.]
通讯作者: Takata T.
Verbal Sightseeing Guidebook for Visualy-impaired by Combining Verbal AR Navigation App. and Sound VR System
  • 批准号:
    19H02265
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $4.33万
  • 财政年份:
    2019
  • 负责人:
    UCHIDA Takashi
  • 依托单位:
Development of Teaching Materials Which Support Co-creation Through Student Dialogue and Cooperation Targeted to Resolving Socioscientific Issues
Sharing System of Guiding Robots for Visually Impaired People
  • 批准号:
    17K18911
  • 项目类别:
    Grant-in-Aid for Challenging Research (Exploratory)
  • 资助金额:
    $4.08万
  • 财政年份:
    2017
  • 负责人:
    UCHIDA Takashi
  • 依托单位:
Voice AR Pedestrian Navigation System for Visually Impaired using NFC Device and Robot Technologies
  • 批准号:
    16H04430
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $7.4万
  • 财政年份:
    2016
  • 负责人:
    UCHIDA Takashi
  • 依托单位:
海外基金