Reguraltory mechanisms of neuronal activity in the superior salivatory nucleus by feeding-related peptides.
Reguraltory mechanisms of neuronal activity in the superior salivatory nucleus by feeding-related peptides.
批准号:
21592361
负责人:
MITOH Yoshihiro
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
The superior salivatory nucleus(SSN) neurons which is the primary parasympathetic center of the submandibular and sublingual salivary glands in rats were excited by orexins, one of feeding-related peptides, from lateral hypothalamic neurons(feeding center). The excitation in SSN neurons was completely inhibited by antagonists for OX1R and OX2R, orexins receptors subtypes. Additionally, SSN neurons showed immunoreactivities for OX1R and OX2R, suggesting that the excitation is mediated by OX1R and OX2R. Orexin-induced excitation in SSN neurons may be involved in abundant salivation in feeding.
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DOI:
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发表时间:
2013
期刊:
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[水谷 諭史, 小橋 基, 藤田 雅子, 美藤 純弘, 松尾 龍二]
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松尾 龍二
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DOI:
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发表时间:
2011
期刊:
影响因子:
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[小橋基, 水谷諭史, 藤田雅子, 美藤純弘, 松尾龍二]
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DOI:
--
发表时间:
2009
期刊:
J Med Invest 57(Suppl)
影响因子:
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[Matsushima A, Ichikawa H, Fujita M, Mitoh Y, Kobashi M, Yamashiro T Marsuo R]
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发表时间:
2009
期刊:
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DOI:
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发表时间:
2012
期刊:
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[庄子幹郎, 佐藤啓子, 雪竹英治, 近藤好夫, 成田由香, 門脇知子, 内藤真理子, 中山浩次, 水谷諭史]
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批准号:17591935
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项目类别:Grant-in-Aid for Scientific Research (C)
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负责人:MITOH Yoshihiro
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依托单位:
海外基金