Approach for the prevention of life-style related diseases from fetal and infancy of life stage

目的：探讨心理社会压力和生活方式对足月低出生体重儿的影响。方法：于2010年12月至2011年9月在日本熊本市进行前瞻性研究。对正常出生体重儿(326例)和足月低出生体重儿(32例)进行比较。使用主观幸福感问卷和母亲的生活方式来评估心理社会压力和生活方式。对正常体重儿母亲和低出生体重儿母亲的上述平均分进行比较，并进行分析。结果：足月出生的低出生体重儿既没有心理社会应激意识，也没有发现与其他生活方式因素的关系。原因是孕期和孕周体重增加所致。但Logistic回归分析显示，足月低出生体重儿的危险因素更多地依赖于孕周，而不是体重的增加。因此，建议孕期的生物学因素和从每天开始的体重控制的影响。

Aim : To determine effect of psychosocial stress and lifestyles on low birthweight(LBW) in full term period. Method : A prospective study was carried out in the Kumamoto city in Japan between December 2010 and September 2011. The normal birthweight infants(326 persons) and the low birthweight infants(32 persons) of full term birth were identified, and both groups were compared. Psychosocial stress and lifestyles were assessed using the Subjective Well-Being Inventory and the lifestyles for mothers. We compared normal-weight infant mothers with LBW infant mothers regard to the above average scores, and made the analysis. Results : As for low-birthweight infant generating in full term birth, neither the psychosocial stress consciousness nor the relation with other life style factors was found. The causes were found by the weight increase in the pregnancy term and gestational weeks. But according to the logistic analysis, the full term low birthweight infant's risk factor was more overwhelmingly dependent on the pregnancy weeks than the weight increase Therefore, the biological factor at the time of conception and the influence of the weight control from every day were suggested.