Approach for the prevention of life-style related diseases from fetal and infancy of life stage

目的：探讨社会心理应激和生活方式对足月低出生体重儿的影响。方法：于2010年12月至2011年9月在日本熊本市进行前瞻性研究。选取正常出生体重儿（326例）和低出生体重儿（32例）进行足月出生比较。使用主观幸福感量表和母亲的生活方式评估心理社会压力和生活方式。我们比较了体重正常的婴儿妈妈和体重低的婴儿妈妈的上述平均得分，并进行了分析。结果：足月低出生体重儿的心理社会应激意识与其他生活方式因素均无关系。其原因是妊娠期和妊娠周的体重增加。但根据logistic分析，足月低出生体重儿的危险因素对妊娠周数的依赖大于对体重增加的依赖，因此建议考虑妊娠时的生物学因素和每天控制体重的影响。

Aim : To determine effect of psychosocial stress and lifestyles on low birthweight(LBW) in full term period. Method : A prospective study was carried out in the Kumamoto city in Japan between December 2010 and September 2011. The normal birthweight infants(326 persons) and the low birthweight infants(32 persons) of full term birth were identified, and both groups were compared. Psychosocial stress and lifestyles were assessed using the Subjective Well-Being Inventory and the lifestyles for mothers. We compared normal-weight infant mothers with LBW infant mothers regard to the above average scores, and made the analysis. Results : As for low-birthweight infant generating in full term birth, neither the psychosocial stress consciousness nor the relation with other life style factors was found. The causes were found by the weight increase in the pregnancy term and gestational weeks. But according to the logistic analysis, the full term low birthweight infant's risk factor was more overwhelmingly dependent on the pregnancy weeks than the weight increase Therefore, the biological factor at the time of conception and the influence of the weight control from every day were suggested.