Development of rapid and accurate data collection method for MX beamline

我们已经开发了使用滨松C10158 DK的连续旋转方法，以实现在同步加速器蛋白质晶体学（MX）光束线上快速准确的数据收集。与传统的CCD振荡法比较表明，CMOS连续旋转法尤其适用于φ切片数据的采集。我们成功地确定了蛋白质的结构使用的CMOS探测器收集的衍射数据，这表明这种数据收集方法是可用的蛋白质晶体学。基于这些结果，我们在SPring-8 MX光束线上安装了CMOS探测器。

We have developed the continuous rotation method using Hamamatsu C10158DK to enable rapid and accurate data collection at the synchrotron protein crystallography(MX) beamlines. Comparison with the conventional oscillation method using a CCD detector showed that the continuous rotation method using the CMOS detector is advantageous especially for the fineφ-sliced data collection. We successfully determined protein structures using diffraction data collected by the CMOS detector, which indicates that this data collection method is usable for protein crystallography. Based on these results, we installed the CMOS detector at the SPring-8 MX beamlines.