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Development of a Variable-Energy, Variable-Intensity, On/Off-Switchable Gamma-Ray Needle Source for Brachytherapy

Development of a Variable-Energy, Variable-Intensity, On/Off-Switchable Gamma-Ray Needle Source for Brachytherapy
开发用于近距离放射治疗的可变能量、可变强度、可开/关切换的伽马射线针源
批准号:
21650126
负责人:
OGURI Yoshiyuki
金额:
$2.18万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
We investigated the feasibility of a new cancer therapy, in which a syringe needle is inserted into the tumor deep inside the patient's body and a proton beam is transported through the needle to a heavy-metal target at the end in order to produce gamma-rays. Since preliminary measurements showed that the gamma-ray intensity was not enough, we used characteristic X-rays instead. After precise alignment, the beam transmission has reached 80% of the value expected from the needle bore size. Ag KX-rays were produced by attaching a Ag target at the end of the needle. Only Ag KX-rays were successfully extracted, since other low-energy X-rays were attenuated by the needle wall.
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DOI: 10.1016/j.nimb.2011.04.073
发表时间: 2011-12
期刊: Nuclear Instruments & Methods in Physics Research Section B-beam Interactions With Materials and Atoms
影响因子: 1.3
作者: [J. Hasegawa;S. Jaiyen;C. Polee;Y. Oguri]
通讯作者: J. Hasegawa;S. Jaiyen;C. Polee;Y. Oguri
ガラスキャピラリーを用いたマイクロPIXE装置の開発
使用玻璃毛细管开发微型 PIXE 装置
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [長谷川純, C.Polee, 福田一志, 小栗慶之]
通讯作者: 小栗慶之
Proton-Beam Transport Experiments through a Syringe Needle for the Development of a Cancer Therapy Using Proton-Induced X-rays
通过注射针进行质子束传输实验,用于开发使用质子诱导 X 射线的癌症疗法
DOI: --
发表时间: 2011
期刊: Bull. Res. Lab. Nucl. Reactor.
影响因子: --
作者: [Yasuhiro Shobayashi, Tetsuya Tanoue, Satoshi Tateshima, Kazuo Tanishita, 谷下一夫, Y. Oguri and J. Hasegawa]
通讯作者: Y. Oguri and J. Hasegawa
Monte-Carlo Simulation of Ion Beam Focusing Using Glancing-Angle Scattering
使用掠射角散射进行离子束聚焦的蒙特卡罗模拟
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [J.Hasegawa, Y.Oguri, S.Jaiyen]
通讯作者: S.Jaiyen
9
    A syringe-needle type monochromatic X-ray source for selective tumor irradiation using X-ray absorption characteristics of sensitizing agents
    • 批准号:
      24650291
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.5万
    • 财政年份:
      2012
    • 负责人:
      OGURI Yoshiyuki
    • 依托单位:
    Cineangiography Using Particle-Induced Dual-Wavelength Pulsed-X-rays for Minimization of Dosages of Contrast Medium and Radiation
    • 批准号:
      20300175
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $12.23万
    • 财政年份:
      2008
    • 负责人:
      OGURI Yoshiyuki
    • 依托单位:
    Development of Radiography Using Proton-Induced X-Rays to Reduce the Dosages of Contrast-Medium and Radiation
    • 批准号:
      17300170
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $10.09万
    • 财政年份:
      2005
    • 负责人:
      OGURI Yoshiyuki
    • 依托单位:
    Measurement of Coulomb Logarithm in Heavy-ion-Plasma Interaction by Using Low-Energy Protons
    • 批准号:
      13480132
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.54万
    • 财政年份:
      2001
    • 负责人:
      OGURI Yoshiyuki
    • 依托单位:
    海外基金