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A control of tooth movement by pharmacologic agent using the coupling mechanism on bone.

A control of tooth movement by pharmacologic agent using the coupling mechanism on bone.
利用骨上的耦合机制通过药物控制牙齿移动。
批准号:
21792106
负责人:
TABUCHI Masako
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
In this study, Reveromycin A(RM-A) was administered to compare and evaluate bone turnover and response of the surrounding boney tissue including osteoblasts. The ability of RM-A to control tooth movement was evaluated. Reveromycin A administration in OPG-/-mice inhibited bone resorption and normalized bone formation. As a result, normal bone turnover was obtained. Moreover, by inhibiting the promoted osteoclastic activity of OPG-/-mice using reveromycin A, excessive osteoblast activity was also inhibited. It is suggested that osteoblast activity was inhibited because some negative factors from osteoclasts to osteoblasts functioned after inhibition of osteoclast activity.
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会议论文
持続的矯正力による歯の移動に対する破骨細胞特異的薬剤(リベロマイシンA)の効果
破骨细胞特异性药物(肝霉素A)对持续正畸力引起的牙齿移动的影响
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [田中美由紀, 宮澤健, 田渕雅子, 藪本貴洋, 門田愛実, 吉廻守, 山根千里, 川谷誠, 長田裕之, 後藤滋巳]
通讯作者: 後藤滋巳
破骨細胞特異的薬剤(Reveromycin A)が実験歯の移動に及ぼす影響
破骨细胞特异性药物(Reveromycin A)对实验性牙齿移动的影响
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [藪本貴洋, 宮澤健, 田渕雅子, 庄司さつき, 田中美由紀, 門田愛実, 川谷誠, 長田裕之, 後藤滋巳]
通讯作者: 後藤滋巳
Bisphosphonate treatment decreases the loss of alveolar bone during experimental tooth movement in OPG-/-mice
双膦酸盐治疗可减少 OPG-/-小鼠实验性牙齿移动过程中牙槽骨的损失
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Masako Tabuchi, Satsuki Shoji, Ken Miyazawa, Takahiro Yabumoto, Miyuki Tanaka, Shigemi Goto]
通讯作者: Shigemi Goto
Experimental tooth movement model considering coupling factor in mice
  • 批准号:
    18791576
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.34万
  • 财政年份:
    2006
  • 负责人:
    TABUCHI Masako
  • 依托单位:
海外基金