Functional analyses of novel autophagy system in immune responses

我们的研究表明，植物免疫反应受膜运输和降解系统的调控。同时建立了烟草BY-2细胞和水稻自噬的实时监测系统，观察了植物细胞在诱导免疫应答过程中自噬的动态变化。此外，我们从水稻中鉴定了几个自噬突变体（Osatgs），对突变体的功能分析表明，自噬在水稻生殖发育中起着关键作用。我们相信这些发现对于提高许多作物的抗逆性是有用的。

Our studies revealed that plant immune responses were regulated by both membrane traffic and degradation system. We also established the real-time monitoring system of autophagy in tobacco BY-2 cells as well as rice, and found the dynamic changes of autophagy during the induction of immune responses in plant cells. In addition, we identified several autophagy mutants (Osatgs) from rice, and functional analyses of mutants revealed that autophagy plays critical roles in during reproductive development in rice. We believe that these findings are useful for improving stress resistance in many crops.