Development o f a cognitive imaging method for geriatrics using tensor based fMRI

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The fundamental algorism to estimate higher order functional connectivity representing the age-dependent characteristics of neuronal network response was developed by implementing over-all computation of the HRF correlation and its tensor analysis. The framework investigated by using qualitative and quantitative modulation of cognitive demand. wasThis method enabled visualization of the functional connectivity as spatially distributed coefficient. It was suggested that longitudinal change of behavioral data might be potentially correlated with age-related change of brain activation.