Elucidation of microbial cyanotoxin degradation mechanism and use the knowledge for aquatic environment treatment application

在本研究中，我们揭示了微生物在微囊藻毒素降解菌中降解微囊藻毒素的酶途径。水环境中mlrA基因的丰度与微囊藻毒素浓度密切相关，因此微囊藻毒素降解菌在微囊藻毒素降解过程中起着关键作用。此外，我们还证实了ADDA诱导mlrA和mlrB的表达，并且微囊藻毒素的环结构与mlrC的表达有关。最后，构建了一种新型的无电解液电化学降解水处理装置。该装置抑制有毒蓝藻的生长，但不抑制其他生物，如动物浮游生物和鱼类。

In the present study, we revealed enzymatic pathway of microbial microcystin degradation in microcystin-degrading bacterium. The abundance of mlrA gene in aquatic environment strongly related to microcystin concentration, thus microcystin-degrading bacteria play a key role in microcystin degradation. Moreover, we confirmed that Adda induce expression of mlrA and mlrB, and cyclic structure of microcystin relate to expression of mlrC. Finally, we have constructed new water treatment apparatus using electrochemical degradation without electrolyte. The apparatus inhibit toxic cyanobacteria growth, but do not inhibit other organism, such as animal plankton and fish.