A study on microplanar beam radiation therapy at high energy X rays(≧1MeV)

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A study on microplanar beam radiation therapy(MRT) has demonstrated the following points : for the animal study at SPring-8, alignment of a collimator is very important to obtain a symmetrical beam profile for irradiation ; hypoxic fraction of tumor cells after MRT treatment was increased, which may explain the selective killing of tumor cells by MRT ; as for a beam width, narrow beam was more effective than wider beam, which suggests that an appropriate beam width must be exist ; and for the X-ray energy, high energy such as 1 MeV was not applicable and the most effective energy will be in the range of 100-250 keV.