Development of Metal -Sulfur Cluster Molecules Leading to Novel Nitrogen Fixation

针对氮气转化的反应中心，研究了由多个金属和硫原子组装而成的过渡金属硫簇作为固氮酶活性中心的模型。采用分步合成路线构建了簇合物骨架，其中四个金属原子和四个硫原子交替位于立方体的拐角。结果表明，该簇合物具有活化配位氮分子的活性。制备了由不同金属元素组成的类似团簇，实现了肼、一氧化碳等在这些团簇上的特异结合和转化。

Aiming at the reaction sites for conversion of nitrogen, transition metal-sulfur clusters were investigated as the models for the active site of nitrogenase, which was assembled from multiple metal and sulfur atoms. Stepwise synthetic routes were applied to construct the cluster skeletons, in which four metal and four sulfur atoms were located alternately at the corners of a cube. Reactivity of the cluster that could activate coordinated nitrogen molecule was revealed. Analogous clusters composed of different metal elements were prepared, and specific binding and conversion of hydrazine and carbon monoxide etc. on these clusters were achieved.