Effect of cortisol diurnal rhythm on emotional memory consolidation

本研究的目的是阐明唾液皮质醇昼夜节律与情绪记忆巩固的关系。在实验当天的4个时间点（8：00、11：00、15：00、20：00）测定唾液皮质醇水平。参与者观看了激动人心的故事，一周后，他们被要求返回实验室，并接受了一次惊喜的记忆测试。故事由三个阶段组成，第二阶段发生了情感唤起的叙述。皮质醇昼夜变化的斜率使用对数转换的皮质醇浓度对样本采集时间的回归计算。只有平坦斜坡组在三个阶段之间没有表现出记忆得分差异。

The aim of this study was to elucidate the relationship between salivary cortisol diurnal rhythm and emotional memory consolidation in healthy subjects. Salivary cortisol levels were measured at four time points(8:00, 11:00, 15:00, 20:00) at the experimental day. The participants viewed emotionally arousing story and one week later they were asked to return to the laboratory and were given a surprise memory test. The story consisted of three phases and emotionally arousing narration occurred during phase 2. The slope of diurnal cortisol variation was calculated using a regression of log-transformed cortisol concentrations on sample collection time. Only the flat slope group did not exhibit a memory score difference among the three phases.