Effect of cortisol diurnal rhythm on emotional memory consolidation

本研究的目的是阐明健康受试者唾液皮质醇昼夜节律与情绪记忆巩固的关系。分别于实验当天8：00、11：00、15：00、20：00测定唾液皮质醇水平。参与者观看了一个激动人心的故事，一周后，他们被要求回到实验室，并接受了一项令人惊讶的记忆测试。故事由三个阶段组成，在第二阶段发生了激动人心的叙述。通过对样本采集时间的对数转换皮质醇浓度的回归计算皮质醇昼夜变化的斜率。只有平坡组在三个阶段之间没有表现出记忆得分的差异。

The aim of this study was to elucidate the relationship between salivary cortisol diurnal rhythm and emotional memory consolidation in healthy subjects. Salivary cortisol levels were measured at four time points(8:00, 11:00, 15:00, 20:00) at the experimental day. The participants viewed emotionally arousing story and one week later they were asked to return to the laboratory and were given a surprise memory test. The story consisted of three phases and emotionally arousing narration occurred during phase 2. The slope of diurnal cortisol variation was calculated using a regression of log-transformed cortisol concentrations on sample collection time. Only the flat slope group did not exhibit a memory score difference among the three phases.